Roxana Elena Mirica
Neuroendocrine tumours (NETs) located in the gastrointestinal tract have had an increased incidence during the past 10 years. Well-differentiated tumour formations located in the small intestine have a slow evolution, with the patients being asymptomatic in the early stages and accidental diagnosis in most cases. In this presentation we report the case of a 55-year-old female patient, with total thyroidectomy performed in 2010 for a papillary thyroid carcinoma, currently undergoing replacement therapy with Euthyrox (75µg / day), asymptomatic. During the ultrasound monitoring of some pre-existing liver haemangiomas, a solid formation was highlighted, vascularised at the level of the last ileal loop. The investigations after the ultrasound, namely, the colonoscopy with examination of the terminal ileum on about 30 cm, PET-CT scan (positron emission tomography/computed tomography), morphological results correlated with the immunophenotypic ones (CHROMO, Synaptophysin, Ki67), have led to the diagnosis of a G1 neuroendocrine tumour located in the terminal ileum. At the same time, the PET-CT scan also showed a left lung nodule, minimally metabolically active, for which excision was recommended, in order to establish the certain diagnosis between a primary formation and a secondary metastasis.
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