Madhav M. Kendre and Mohammad A. Baseer
In the present investigation, a series of some novel 3-[substituted-2-hydroxy-phenyl]-5-(4’-dimethylamino-phenyl)-2-pyrazoline-1-carboxaldehydes (2a-j) have been synthesized by the treatment of 1-(substituted-2-hydroxy-phenyl)-3-(4’-dimethylamino-phenyl)-prop-2-en-1-one (chalcones) (1a-j) with hydrazine hydrate in hot formic acid using ethanol solvent by conventional method. In 85-95% yield with high purity, the structure of newly synthesized compounds was confirmed by the IR, 1H NMR and Mass spectral analysis. All these newly synthesized compounds were evaluated for their in vitro antimicrobial activity. Most of the compounds showed potent activity.
English 
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Telugu